Gwern — Behavior Genetics↗

It is of course possible for a new mutation to be fitter or for the environment to change and render some alternative more fit. This is sometimes true, but it is overwhelmingly usually false.

The idea of iterated embryo selection —conducing multiple generations of embryo selection in a petri dish by exploiting gametogenesis or stem cells—has a complicated history.

Computer “Generalized Problematic Internet Use Scale 2” (GPIUS-2) total 0.00 Hahn et al 2017 Computer “Problematic Internet Use Scale” (PIUS) total 0.

Because of the potential to select for arbitrarily many generations, IES (or equally powerful methods like genome synthesis) can deliver arbitrarily large net gains—raising the question of what one...

In MLP:FiM, the 3 pony races sometimes bear offspring of other pony races; I review 4 complicated Mendelian models attempting to explain this, and note that a standard polygenic liability-threshold...

Frank Herbert’s SF Dune series features as a central mechanic a multi-millennium human eugenics breeding program by the Bene Gesserit, which produces the main character, Paul Atreides, with...

Cloning is widely used in animal & plant breeding despite steep costs due to its advantages; more unusual recent applications include creating entire polo horse teams and reported trials of cloning...

What is most interesting is the intellectual history we can extract from it in terms of inventing heritability and as important, one of the inventions of progress in the gradual realization that...

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Can deer evolve under the selection pressure of car accidents to learn to avoid roads? Probably, but it’ll take a long time. I’ve noticed while driving many deer corpses over the years.